Chemical genetics: receptor–ligand pairs for rapid manipulation of neuronal activity
نویسندگان
چکیده
Toward the functional dissection of neuronal circuits, a number of new genetic tools have been developed that enable rapid and reversible manipulation of genetically defined neuronal subtypes in intact mammalian brain circuits. Alongside the breakthrough technology of optogenetics, receptor-ligand pairs provide complementary approaches to modulate neuronal activity using chemical genetics.
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عنوان ژورنال:
- Current Opinion in Neurobiology
دوره 22 شماره
صفحات -
تاریخ انتشار 2012